Turning Complex Biomedical Data Into Clear, Actionable Insight

BMQuark LLC helps research labs, biotech and healthcare organizations extract reliable results from medical images and biomedical data โ€” faster, and with the rigor of NIH-grade research.

Start a Project See Our Services

The Problems We Solve

Biomedical imaging and data teams often hit the same walls. We remove them.

๐Ÿงฉ

No in-house AI/imaging expertise

Your team has great biology or clinical knowledge, but lacks deep learning and computer vision specialists to build reliable image analysis pipelines.

โณ

Manual annotation is too slow

Segmenting tumors, organs, or cells by hand across hundreds of scans eats months of researcher time and introduces inconsistency.

๐Ÿ“Š

Messy, unscalable data pipelines

Raw imaging and multi-modal datasets (CT/PET/MRI, pathology slides, omics) pile up without a reproducible pipeline to clean, align, and analyze them.

๐Ÿ”ฌ

Results that don't hold up to review

Quick-and-dirty scripts don't survive peer review or regulatory scrutiny. You need methods that are validated, documented, and reproducible.

What We Offer

End-to-end biomedical data and imaging services, built on a decade of academic and NIH research experience.

1

Medical Image Analysis & Segmentation

Automated, deep-learning-based segmentation and co-registration for CT, PET-CT, MRI and other multi-modal imaging data.

  • Tumor / organ segmentation
  • Multi-modality co-segmentation
  • Treatment response prediction
2

Custom AI / Deep Learning Model Development

Purpose-built computer vision models for classification, detection, and quantitative analysis of biomedical images.

  • Model design & training
  • Transfer learning for small datasets
  • Model validation & benchmarking
3

Biomedical Data Processing & Pipelines

Scalable, reproducible pipelines to clean, curate, and structure large imaging and biomedical datasets.

  • Data curation & preprocessing
  • Feature extraction
  • Pipeline automation
4

Research & Algorithm Consulting

Hands-on collaboration to design analysis strategies, troubleshoot methods, and support publication-ready results.

  • Study design support
  • Method development
  • Manuscript-ready results
ZZ

Led by a Researcher, Built for Results

BMQuark LLC was founded by Dr. Zisha Zhong, who serves as core developer and lead scientist. Dr. Zhong holds a Ph.D. in Pattern Recognition and Artificial Intelligence from the Institute of Automation, Chinese Academy of Sciences, with a research focus on image processing, image analysis, and computer vision.

Between 2022 and 2025, Dr. Zhong conducted postdoctoral research at the National Institutes of Health (NIH), applying machine learning to biomedical data analysis. Prior work has included PET-CT tumor co-segmentation, deep learning-based cancer treatment response prediction, and image segmentation research published in venues such as Medical Physics and IEEE ISBI.

That combination of academic rigor and applied biomedical experience is what BMQuark brings to every client project.

Ph.D., CASIA NIH Postdoc 2022โ€“2025 Computer Vision Medical Imaging

Proven at NIH Scale

A look at a system Dr. Zhong built and led during his NIH postdoctoral research โ€” now live in production.

NATIONAL CANCER INSTITUTE ยท NIH

HERE โ€” H&E Retrieval Engine

Center for Cancer Research, Cancer Data Science Lab (Jiang Lab)

21.2 TB
Whole-slide image database searched
12.1 GB
Memory index for near-instant retrieval
101
Benchmark queries, pathologist-validated

The Challenge

Pathologists and researchers had no fast way to search terabyte-scale H&E slide archives by image similarity โ€” the pathology-image equivalent of a sequence search tool like BLAST simply didn't exist at this scale.

The Approach

Built an AI-based image encoding pipeline paired with a hierarchical skip-indexing structure, enabling searches across multiple tumor histopathology cohorts (NCI Lab of Pathology, TCGA, CPTAC) from a single desktop-class machine โ€” no specialized infrastructure required.

The Result

Retrieval accuracy validated through blinded scoring by practicing pathologists, outperforming existing image retrieval tools. The system also links image features to gene expression and molecular pathways via spatial transcriptomics โ€” and is live in production today.

View Live App โ†’ Read the Preprint โ†’

This project was developed by Dr. Zhong in his official capacity as a postdoctoral researcher at the National Cancer Institute (NCI), National Institutes of Health (NIH), and is presented here for informational purposes to describe his prior research experience. Its inclusion on this page does not imply endorsement, sponsorship, or affiliation of BMQuark LLC by NIH, NCI, or the U.S. Government.

How We Work

A simple, transparent process from first conversation to delivered results.

1

Discovery Call

We learn about your data, goals, and constraints.

2

Scoping & Proposal

Clear deliverables, timeline, and pricing.

3

Development & Iteration

Regular check-ins and progress updates.

4

Delivery & Support

Validated results plus documentation and follow-up support.

Let's Talk About Your Data

Whether it's a single dataset or an ongoing research partnership, we'd love to hear what you're working on.

contact@bmquark.com